Rapid advances in drug discovery have led to the identification of a number of compounds with good therapeutic potential.

The design of accurate and robust analytical methodology is instrumental to developing orally inhaled and nasal drug products (OINDPs) and their appropriate control programmes.

A hydrophilic matrix tablet is the simplest and most cost-effective method of fabricating an extended release (ER) solid oral dosage form.

Proteins are involved in many biological processes in the human body, as well as in micro-organisms such as bacteria and viruses, and, as such, deserve to be regarded as the 'work horses of the cell'.

DPIs: challenges for next generation therapies 01 April 2007

There have been significant advances, especially in understanding the role of carrier properties on the aerosol performance of the API.

Lactose, in particular alpha-lactose monohydrate, is typically used as 'the' carrier in dry powder inhalers. Even though these often tailored materials allow the delivery of medicines to the body in doses that are much lower than by 'conventional' solid dosage forms, the use of this excipient in this application is posing characterization and regulatory challenges to both suppliers and users.

Terpenes are widely used in topical preparations. This paper focuses on the skin penetration of terpenes depending on their physicochemical properties and influence of the type of dermatological vehicle that was used. The structure of human skin and the skin penetration process is also briefly described.

This paper focuses on the skin penetration of terpenes depending on their physicochemical properties and influence of the type of dermatological vehicle that was used.

Nanoparticulate drug carriers include a class of particles made of polymers or lipids that — because of their size and chemical composition —permit systemic and local treatment.