http://www.ptasiapacific.com/ptasiapacific Pharmaceutical Technology Asia Pacific 2008-08-07T21:55:50Z http://www.ptasiapacific.com/ptasiapacific/Latest+News/Asia-is-the-place-to-be/ArticleStandard/Article/detail/533822?ref=25 Asia is the new hotspot for clinical trials, according to an analysis by Citeline (NY, USA), with South Korea seeing the largest gains in oncology trial sites in 2007 compared with figures for 2004. 2008-08-04T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/322008/533822null HTML http://www.ptasiapacific.com/ptasiapacific/Latest+News/Treatment-for-respiratory-virus-in-Asia/ArticleStandard/Article/detail/525101?ref=25 An exclusive alliance aims to develop and commercialize a treatment for respiratory syncytial virus infection in Japan and other major markets in Asia. 2008-06-20T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/252008/525101null HTML http://www.ptasiapacific.com/ptasiapacific/Latest+News/India-and-China-becoming-RampD-centres/ArticleStandard/Article/detail/524673?ref=25 Indian and Chinese scientists are rapidly developing the ability to innovate and create more intellectual property because of the movement of R&D to their countries, according to a US study. 2008-06-18T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/252008/524673null HTML http://www.ptasiapacific.com/ptasiapacific/PTAP-2008-Readersip-survey/ArticleStandard/Article/detail/522443?ref=25 PTAP 2008 Readership survey 2008-06-09T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/242008/522443null HTML http://www.ptasiapacific.com/ptasiapacific/Online+Exclusives/China-captivates-the-clinical-trial-industry/ArticleStandard/Article/detail/521397?ref=25 China is generating huge interest as a destination for outsourced clinical trials, particularly since the US consulting firm AT Kearney ranked it above India in 2007...Read More 2008-06-03T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/232008/521397null HTML http://www.ptasiapacific.com/ptasiapacific/Online+Exclusives/The-rise-of-Asia/ArticleStandard/Article/detail/521392?ref=25 There is no doubt that the shift of pharmaceutical business is tilting towards Asia. With the industry growing at high speed, Asia is being hailed as 'the pharmaceutical hub'...Read More 2008-06-03T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/232008/521392null HTML http://www.ptasiapacific.com/ptasiapacific/Editor%27s+Comment/The-new-kid-on-the-block/ArticleStandard/Article/detail/519361?ref=25 While all eyes are on China and India as the next big players of the pharma and biopharma world, there is a "new kid on the block": the Middle East states. 2008-06-01T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/222008/519361null XML http://www.ptasiapacific.com/ptasiapacific/Regulatory/FDA-under-fire/ArticleStandard/Article/detail/519363?ref=25 Yet again, FDA has come under siege for failing to inspect a Chinese manufacturing facility. 2008-06-01T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/222008/519363null XML http://www.ptasiapacific.com/ptasiapacific/Regulatory/Down-Unders-PBS-going-down/ArticleStandard/Article/detail/519369?ref=25 The PBS's ability to keep drug prices low seems to be what catches the attention of the global pharma industry. In general, prices in Australia are three to four times cheaper compared with the US. 2008-06-01T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/222008/519369null XML http://www.ptasiapacific.com/ptasiapacific/PAT/Changing-Times/ArticleStandard/Article/detail/519368?ref=25 PAT ensures the continuous control of processes and the timely availability of quality products to market, which results in satisfied customers. 2008-06-01T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/222008/519368/Barshikar_flash.jpg XML http://www.ptasiapacific.com/ptasiapacific/Flash+Articles/The-recovery-mission-coping-with-validation-failur/ArticleStandard/Article/detail/519364?ref=25 Choosing to optimize the test methods may have greatest effect on future test method performance, but this is usually the most expensive recovery process... and may require significant time to complete. 2008-06-01T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/222008/519364/Krause_flash.jpg XML http://www.ptasiapacific.com/ptasiapacific/Drug+Delivery/PEG-biopharmas-wonder-polymer/ArticleStandard/Article/detail/519367?ref=25 Proteins are involved in many biological processes in the human body, as well as in micro-organisms such as bacteria and viruses, and, as such, deserve to be regarded as the 'work horses of the cell'. 2008-06-01T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/222008/519367/Pradeep_flash.jpg XML http://www.ptasiapacific.com/ptasiapacific/Latest+News/Nanparticles-aid-cancer-detection/ArticleStandard/Article/detail/521401?ref=25 Researchers have created the smallest magnetic nanoparticles to date that can be used to detect cancer cells...Read More 2008-06-01T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/232008/521401null HTML http://www.ptasiapacific.com/ptasiapacific/News/News/ArticleStandard/Article/detail/519362?ref=25 FDA will establish eight full-time positions at the US Diplomatic posts in China. 2008-06-01T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/222008/519362null XML http://www.ptasiapacific.com/ptasiapacific/Information+Technology/Jake-Sorofman/ArticleStandard/Article/detail/519370?ref=25 You have many years of experience in marketing and business development. What are the most significant changes you have observed in this time? 2008-06-01T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/222008/519370null XML http://www.ptasiapacific.com/ptasiapacific/Latest+News/Australia-and-the-US-outperform-Europe-in-osteopor/ArticleStandard/Article/detail/521396?ref=25 A global study has revealed that there is more screening and treatment for osteoporosis in Australia and the US compared with Europe...Read More 2008-05-26T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/232008/521396null HTML http://www.ptasiapacific.com/ptasiapacific/News/News/ArticleStandard/Article/detail/505857?ref=25 The catch-up game; Generics central 2008-03-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/132008/505857null XML http://www.ptasiapacific.com/ptasiapacific/Biopharmaceuticals/Biotechnology-the-Victorian-way/ArticleStandard/Article/detail/505866?ref=25 ... Victoria is exceptionally well-placed to translate research discoveries to other sectors of the economy. 2008-03-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/132008/505866/Melbourne_flash.jpg XML http://www.ptasiapacific.com/ptasiapacific/Biopharmaceuticals/Economy-by-design-for-biopharmaceutical-chromatogr/ArticleStandard/Article/detail/505860?ref=25 It is important to always evaluate new technologies, especially those that enhance patient safety, increase productivity and reduce overall cost while still maintaining production of a high-quality product. 2008-03-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/132008/505860null XML http://www.ptasiapacific.com/ptasiapacific/News/News/ArticleStandard/Article/detail/505858?ref=25 Japanese approval for advanced treatments 2008-03-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/132008/505858null XML http://www.ptasiapacific.com/ptasiapacific/Manufacturing+and+Processing/Catalyst-screening/ArticleStandard/Article/detail/505864?ref=25 The time-to-market constraints associated with modern drug development restricts the methodologies and reactions that can be used to make an API. In addition, there are also health and safety issues coupled with environmental factors to consider. An ideal reaction would use an innocuous catalyst to convert all of the substrate to the desired product. However, we are far from this ideal situation. A catalytic reaction has many advantages compared with one that uses a stoichiometric reagent: one molecule of catalyst can produce many molecules of product. This decreases the amount of reagent needed, which can have positive consequences for waste and cost. 2008-03-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/132008/505864null XML http://www.ptasiapacific.com/ptasiapacific/Information+Technology/Are-you-actively-managing-your-data/ArticleStandard/Article/detail/505867?ref=25 Getting a clear view of business performance can be cumbersome, time-consuming and even nigh-on impossible. 2008-03-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/132008/505867null XML http://www.ptasiapacific.com/ptasiapacific/Validation/The-transformation-and-future-trends-of-laboratory/ArticleStandard/Article/detail/505862?ref=25 Historically, the main purpose of laboratory information management systems (LIMS) has been to track and manage samples in the laboratory. LIMS originated nearly 30 years ago as a rudimentary method of automating manual, error-prone processes in the laboratory and, with the growth in adoption of technology, became the de facto benchmark for laboratory control and management. 2008-03-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/132008/505862null XML http://www.ptasiapacific.com/ptasiapacific/Validation/Achieving-GLP-compliance-through-deployment-of-LIM/ArticleStandard/Article/detail/480668?ref=25 A checklist of how to achieve regulatory compliance by validation of laboratory information management systems. Validation costs and cost-effective validation strategies are considered for pharmaceutical manufacturers to validate their systems and maintain a validated state for continued compliance. 2007-12-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/512007/480668/main_main.jpg http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/512007/480668null XML http://www.ptasiapacific.com/ptasiapacific/News/News/ArticleStandard/Article/detail/480666?ref=25 Asia is not a homogenous landscape. It is made up of countries with different cultures, practices and rules. 2007-12-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/512007/480666null XML http://www.ptasiapacific.com/ptasiapacific/News/ArticleStandard/Article/detail/480664?ref=25 Metastatic treatment for Japan; Improved supply chain; ISO for Fortitech 2007-12-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/512007/480664null XML http://www.ptasiapacific.com/ptasiapacific/Biopharmaceuticals/Avoiding-pitfalls-in-scaling-up-biopharmaceutical-/ArticleStandard/Article/detail/480669?ref=25 The scale-up of manufacturing processes to clinical production can be complicated and expensive, with many issues to consider. This article describes some of the common and less obvious pitfalls encountered by biopharmaceutical companies when scaling up protein production processes, and how to avoid them. 2007-12-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/512007/480669null XML http://www.ptasiapacific.com/ptasiapacific/Biopharmaceuticals/New-Zealands-biopharm-boom/ArticleStandard/Article/detail/480667?ref=25 New Zealand's unique genetic and geological diversity is converging with its scientific expertise to create a fast-growing biotechnology industry. 2007-12-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/512007/480667null XML http://www.ptasiapacific.com/ptasiapacific/Supply+Chain/Stacking-the-chips-against-counterfeits/ArticleStandard/Article/detail/480670?ref=25 Is consolidated distribution the key to combating counterfeit drugs and parallel imports? 2007-12-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/512007/480670null XML http://www.ptasiapacific.com/ptasiapacific/Editor%27s+Comment/Global-perception/ArticleStandard/Article/detail/480663?ref=25 How do you think Asian manufacturing is viewed in Europe and the US (your two largest export markets)? Until recently, it was mostly value for money; but all that has changed with a spate of public relations disasters as all manner of goods, from toys and baby milk through to pet food and toothpaste, have been recalled for various issues (the current favourite is high levels of lead in children's products). Now, Asian manufacturers, particularly those in China, are viewed with some trepidation. Pharmaceuticals haven't escaped the spotlight either, but the onus is now on you to ensure the message reaches the west — products manufactured in this region are safe to use; we must change how Asian companies are perceived from cheap and cheerful to good quality at low prices. 2007-12-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/512007/480663null XML http://www.ptasiapacific.com/ptasiapacific/4-page-media-kit-for-Pharmaceutical-Technology-Asi/ArticleStandard/Article/detail/464905?ref=25 4 page media kit for Pharmaceutical Technology Asia Pacific Magazine 2007-10-12T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/412007/464905null PDF http://www.ptasiapacific.com/ptasiapacific/Supply+Chain/Parallel-trade-still-a-grey-area-for-GSK/ArticleStandard/Article/detail/439787?ref=25 The refusal to sell was motivated by a desire to maximize GSK's profits, and GSK had not shown that not having these profits would prejudice consumers by restricting GSK's R&D. 2007-06-01T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/272007/439787null XML http://www.ptasiapacific.com/ptasiapacific/PAT/Integrating-PAT-with-MES/ArticleStandard/Article/detail/439779?ref=25 Understandably, the thought of implementing a closed-loop PAT strategy throughout the global enterprise and for all products can keep pharmaceutical executives awake at night. 2007-06-01T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/272007/439779null XML http://www.ptasiapacific.com/ptasiapacific/Biopharmaceuticals/Improving-productivity-in-downstream-processing/ArticleStandard/Article/detail/439775?ref=25 Improved feedstream titres are driving a demand for increased downstream processing productivity as manufacturers seek to lower the costs of monoclonal antibodies (MAbs). The unique selectivity of protein A has enabled platform technologies for MAb purification. Platform technologies and chromatography resin improvements can help manufacturers achieve rapid and economical process development and scale-up. A multiprong approach can enable downstream process scientists to enhance productivity. 2007-06-01T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/272007/439775null XML http://www.ptasiapacific.com/ptasiapacific/Manufacturing+and+Processing/Designing-a-winning-process-development-strategy/ArticleStandard/Article/detail/439781?ref=25 2007-06-01T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/272007/439781null XML http://www.ptasiapacific.com/ptasiapacific/News/News/ArticleStandard/Article/detail/439770?ref=25 While Novartis is not new to Asia, the Swiss-based company is ramping up efforts to penetrate further into the burgeoning pharmaceutical market by coming up with ingenious ways to cultivate trust and rapport. 2007-06-01T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/272007/439770null XML http://www.ptasiapacific.com/ptasiapacific/Validation/Dissolution-testing-and-good-manufacturing-practic/ArticleStandard/Article/detail/422107?ref=25 Missed or late calibration dates can accumulate, and even if the equipment is labelled appropriately, it can suggest poor management of resources and priorities. 2007-04-01T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/172007/422107/Gray_flash.jpg XML http://www.ptasiapacific.com/ptasiapacific/APIs/DPIs-challenges-for-next-generation-therapies/ArticleStandard/Article/detail/422106?ref=25 There have been significant advances, especially in understanding the role of carrier properties on the aerosol performance of the API. 2007-04-01T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/172007/422106/Chan_thumbnail.jpg http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/172007/422106/Chan_flash.jpg XML http://www.ptasiapacific.com/ptasiapacific/PTAP-Advert-Specs/ArticleStandard/Article/detail/415059?ref=25 PTAP Advert Specs 2007-03-29T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/132007/415059null PDF http://www.ptasiapacific.com/ptasiapacific/PTAP-Editorial-Calendar/ArticleStandard/Article/detail/415062?ref=25 PTAP Editorial Calendar 2007-03-29T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/132007/415062null PDF http://www.ptasiapacific.com/ptasiapacific/Author-Guidelines/ArticleStandard/Article/detail/414400?ref=25 Author Guidelines 2007-03-27T04:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/132007/414400null PDF http://www.ptasiapacific.com/ptasiapacific/News/News/ArticleStandard/Article/detail/418922?ref=25 Taiwan's Bureau of National Health Insurance (BNHI) has issued its fifth round of price adjustments for prescription medicine; a cut that represents a compromise from earlier plans. The government's initial proposal was to lower prices of 562 pharmaceutical products. 2007-03-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/418922null XML http://www.ptasiapacific.com/ptasiapacific/Outsourcing/Clinical-research-in-India/ArticleStandard/Article/detail/418944?ref=25 The acceptance of India as a clinical research hub by the global pharmaceutical fraternity has led to a plethora of business opportunities for a variety of ancillary businesses. In this article, the author attempts to highlight the dynamics of each of these business prospects in India. 2007-03-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/418944/main_main.jpg http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/418944null XML http://www.ptasiapacific.com/ptasiapacific/Manufacturing+and+Processing/Improving-speed-and-quality-in-vaccine-production/ArticleStandard/Article/detail/422108?ref=25 While single-use technologies can be used for filtration, storage and at connection points in egg-based vaccine production, their use multiplies in cell-based applications. 2007-03-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/172007/422108/Pora_flash.jpg XML http://www.ptasiapacific.com/ptasiapacific/Biopharmaceuticals/Virus-removal-by-filtration-points-to-consider/ArticleStandard/Article/detail/418947?ref=25 Virus safety of biotech-and plasma-derived therapeutics is ensured through complementary manufacturing and quality control measures that include the control and monitoring of raw materials, the validation and implementation of effective virus clearance technology and the monitoring of final filled product for the presence of virus. Virus filtration, which is considered a robust and effective virus clearance technology, is a common unit operation in the manufacture of biologicals. In this article, we review the points that must be considered when selecting a virus-retentive filter. The areas covered include regulatory considerations; selecting, optimizing and validating a virus filtration step; and process scale implementation — areas that are critical to users of virus filters. 2007-03-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/418947/main_main.jpg http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/418947null XML http://www.ptasiapacific.com/ptasiapacific/Analytical/A-Raman-spectroscopic-method-to-monitor-magnesium-/ArticleStandard/Article/detail/418929?ref=25 2007-03-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/418929/main_main.jpg http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/418929null XML http://www.ptasiapacific.com/ptasiapacific/Drug+Delivery/Carriers-for-DPIs-formulation-and-regulatory-chall/ArticleStandard/Article/detail/418950?ref=25 Lactose, in particular alpha-lactose monohydrate, is typically used as 'the' carrier in dry powder inhalers. Even though these often tailored materials allow the delivery of medicines to the body in doses that are much lower than by 'conventional' solid dosage forms, the use of this excipient in this application is posing characterization and regulatory challenges to both suppliers and users. 2007-03-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/418950/main_main.jpg http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/418950null XML http://www.ptasiapacific.com/ptasiapacific/APIs/The-Asian-pharmaceutical-market/ArticleStandard/Article/detail/418943?ref=25 Until recently, activity [in Asia] was driven by India and China, but there is now a surge in the rest of Asia as well. 2007-03-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/418943null XML http://www.ptasiapacific.com/ptasiapacific/Ingredients/Applications-of-Raman-spectroscopy-in-aqueous-envi/ArticleStandard/Article/detail/417892?ref=25 Raman spectroscopy has become a commonly used technique for physicochemical analysis that possesses many advantages over other analytical techniques. It is a very attractive characterization tool, not least because it enables measurements in water. However, very few examples of its application in an aqueous environment exist in literature. This paper provides some recent applications of Raman spectroscopy in pharmaceutical material and process characterization when water is present. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417892null XML http://www.ptasiapacific.com/ptasiapacific/Formulation/Applications-of-Raman-spectroscopy-in-aqueous-envi/ArticleStandard/Article/detail/417865?ref=25 Raman spectroscopy has become a commonly used technique for physicochemical analysis that possesses many advantages over other analytical techniques. It is a very attractive characterization tool, not least because it enables measurements in water. However, very few examples of its application in an aqueous environment exist in literature. This paper provides some recent applications of Raman spectroscopy in pharmaceutical material and process characterization when water is present. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417865null XML http://www.ptasiapacific.com/ptasiapacific/APIs/Skin-penetration-of-terpenes/ArticleStandard/Article/detail/416456?ref=25 Terpenes are widely used in topical preparations. This paper focuses on the skin penetration of terpenes depending on their physicochemical properties and influence of the type of dermatological vehicle that was used. The structure of human skin and the skin penetration process is also briefly described. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416456null XML http://www.ptasiapacific.com/ptasiapacific/Static-electricity-in-solid-dosage-manufacturing/ArticleStandard/Article/detail/417829?ref=25 The same phenomena that create lightning and thunderstorms are around us every day, producing incredibly high voltages, which cause sparks and shocks. Static electricity is a mighty force. Each year excessive electrical charge build cause explosions in the grain industry.1 Look around any flammable storage area and you will see both grounding bars on the wall and cables, from the grounding bars connected to the drums of solvents. Take any material safety data sheet (MSDS) for a powder and look in section V; it highlights that any dry powder has the potential to attract and store a charge. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417829null XML http://www.ptasiapacific.com/ptasiapacific/Ingredients/Static-electricity-in-solid-dosage-manufacturing/ArticleStandard/Article/detail/417894?ref=25 The same phenomena that create lightning and thunderstorms are around us every day, producing incredibly high voltages, which cause sparks and shocks. Static electricity is a mighty force. Each year excessive electrical charge build cause explosions in the grain industry.1 Look around any flammable storage area and you will see both grounding bars on the wall and cables, from the grounding bars connected to the drums of solvents. Take any material safety data sheet (MSDS) for a powder and look in section V; it highlights that any dry powder has the potential to attract and store a charge. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417894null XML http://www.ptasiapacific.com/ptasiapacific/Manufacturing+and+Processing/Static-electricity-in-solid-dosage-manufacturing/ArticleStandard/Article/detail/417903?ref=25 The same phenomena that create lightning and thunderstorms are around us every day, producing incredibly high voltages, which cause sparks and shocks. Static electricity is a mighty force. Each year excessive electrical charge build cause explosions in the grain industry.1 Look around any flammable storage area and you will see both grounding bars on the wall and cables, from the grounding bars connected to the drums of solvents. Take any material safety data sheet (MSDS) for a powder and look in section V; it highlights that any dry powder has the potential to attract and store a charge. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417903null XML http://www.ptasiapacific.com/ptasiapacific/Ingredients/Graphical-representation-of-formulation-data-for-a/ArticleStandard/Article/detail/417891?ref=25 Parallel coordinate geometry (PCG) is a graphical methodology that enables multidimensional data to be displayed in two dimensions. Such methods are capable of allowing the formulator insight into the critical relationships and interactions within a formulation, and to explore the effect of formulation variations without recourse to detailed statistical analysis. This article describes the application of two PCG programs — Curvaceous Visual Explorer and Curvaceous Response Surface Visualiser — to evaluate a topical gel formulation. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417891null XML http://www.ptasiapacific.com/ptasiapacific/Ingredients/Skin-penetration-of-terpenes/ArticleStandard/Article/detail/417893?ref=25 Terpenes are widely used in topical preparations. This paper focuses on the skin penetration of terpenes depending on their physicochemical properties and influence of the type of dermatological vehicle that was used. The structure of human skin and the skin penetration process is also briefly described. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417893null XML http://www.ptasiapacific.com/ptasiapacific/Dosage+Forms/Disposable-bioreactors-based-on-wave-agitation-tec/ArticleStandard/Article/detail/416878?ref=25 Over the past decade, disposable technologies have become a reality in biotech processes. The use of disposables in research and manufacturing allows high flexibility. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416878null XML http://www.ptasiapacific.com/ptasiapacific/APIs/Applications-of-Raman-spectroscopy-in-aqueous-envi/ArticleStandard/Article/detail/416455?ref=25 Raman spectroscopy has become a commonly used technique for physicochemical analysis that possesses many advantages over other analytical techniques. It is a very attractive characterization tool, not least because it enables measurements in water. However, very few examples of its application in an aqueous environment exist in literature. This paper provides some recent applications of Raman spectroscopy in pharmaceutical material and process characterization when water is present. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416455null XML http://www.ptasiapacific.com/ptasiapacific/Dosage+Forms/Disposable-bioreactors-based-on-wave-agitation-tec/ArticleStandard/Article/detail/416870?ref=25 Over the past decade, disposable technologies have become a reality in biotech processes. The use of disposables in research and manufacturing allows high flexibility. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416870null XML http://www.ptasiapacific.com/ptasiapacific/Drug+Delivery/Skin-penetration-of-terpenes/ArticleStandard/Article/detail/417837?ref=25 Terpenes are widely used in topical preparations. This paper focuses on the skin penetration of terpenes depending on their physicochemical properties and influence of the type of dermatological vehicle that was used. The structure of human skin and the skin penetration process is also briefly described. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417837null XML http://www.ptasiapacific.com/ptasiapacific/Biopharmaceuticals/Cell-culture-must-go-vegetarian/ArticleStandard/Article/detail/416864?ref=25 Brain and heart broth is still used in path labs, but, when it comes to biopharmaceutical manufacturing, cells are having to learn to do without animal components whenever possible. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416864null XML http://www.ptasiapacific.com/ptasiapacific/Manufacturing+and+Processing/Applications-of-Raman-spectroscopy-in-aqueous-envi/ArticleStandard/Article/detail/417902?ref=25 Raman spectroscopy has become a commonly used technique for physicochemical analysis that possesses many advantages over other analytical techniques. It is a very attractive characterization tool, not least because it enables measurements in water. However, very few examples of its application in an aqueous environment exist in literature. This paper provides some recent applications of Raman spectroscopy in pharmaceutical material and process characterization when water is present. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417902null XML http://www.ptasiapacific.com/ptasiapacific/Dosage+Forms/Cell-culture-must-go-vegetarian/ArticleStandard/Article/detail/416871?ref=25 Brain and heart broth is still used in path labs, but, when it comes to biopharmaceutical manufacturing, cells are having to learn to do without animal components whenever possible. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416871null XML http://www.ptasiapacific.com/ptasiapacific/Formulation/Graphical-representation-of-formulation-data-for-a/ArticleStandard/Article/detail/417864?ref=25 Parallel coordinate geometry (PCG) is a graphical methodology that enables multidimensional data to be displayed in two dimensions. Such methods are capable of allowing the formulator insight into the critical relationships and interactions within a formulation, and to explore the effect of formulation variations without recourse to detailed statistical analysis. This article describes the application of two PCG programs — Curvaceous Visual Explorer and Curvaceous Response Surface Visualiser — to evaluate a topical gel formulation. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417864null XML http://www.ptasiapacific.com/ptasiapacific/Manufacturing+and+Processing/Disposable-bioreactors-based-on-wave-agitation-tec/ArticleStandard/Article/detail/417901?ref=25 Over the past decade, disposable technologies have become a reality in biotech processes. The use of disposables in research and manufacturing allows high flexibility. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417901null XML http://www.ptasiapacific.com/ptasiapacific/Analytical/Graphical-representation-of-formulation-data-for-a/ArticleStandard/Article/detail/416619?ref=25 Parallel coordinate geometry (PCG) is a graphical methodology that enables multidimensional data to be displayed in two dimensions. Such methods are capable of allowing the formulator insight into the critical relationships and interactions within a formulation, and to explore the effect of formulation variations without recourse to detailed statistical analysis. This article describes the application of two PCG programs — Curvaceous Visual Explorer and Curvaceous Response Surface Visualiser — to evaluate a topical gel formulation. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416619null XML http://www.ptasiapacific.com/ptasiapacific/Clean+Rooms/Disposable-bioreactors-based-on-wave-agitation-tec/ArticleStandard/Article/detail/417813?ref=25 Over the past decade, disposable technologies have become a reality in biotech processes. The use of disposables in research and manufacturing allows high flexibility. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417813null XML http://www.ptasiapacific.com/ptasiapacific/Analytical/Applications-of-Raman-spectroscopy-in-aqueous-envi/ArticleStandard/Article/detail/416620?ref=25 Raman spectroscopy has become a commonly used technique for physicochemical analysis that possesses many advantages over other analytical techniques. It is a very attractive characterization tool, not least because it enables measurements in water. However, very few examples of its application in an aqueous environment exist in literature. This paper provides some recent applications of Raman spectroscopy in pharmaceutical material and process characterization when water is present. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416620null XML http://www.ptasiapacific.com/ptasiapacific/Biopharmaceuticals/Disposable-bioreactors-based-on-wave-agitation-tec/ArticleStandard/Article/detail/416861?ref=25 Over the past decade, disposable technologies have become a reality in biotech processes. The use of disposables in research and manufacturing allows high flexibility. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416861null XML http://www.ptasiapacific.com/ptasiapacific/Formulation/Static-electricity-in-solid-dosage-manufacturing/ArticleStandard/Article/detail/417867?ref=25 The same phenomena that create lightning and thunderstorms are around us every day, producing incredibly high voltages, which cause sparks and shocks. Static electricity is a mighty force. Each year excessive electrical charge build cause explosions in the grain industry.1 Look around any flammable storage area and you will see both grounding bars on the wall and cables, from the grounding bars connected to the drums of solvents. Take any material safety data sheet (MSDS) for a powder and look in section V; it highlights that any dry powder has the potential to attract and store a charge. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417867null XML http://www.ptasiapacific.com/ptasiapacific/Dosage+Forms/Cell-culture-must-go-vegetarian/ArticleStandard/Article/detail/416879?ref=25 Brain and heart broth is still used in path labs, but, when it comes to biopharmaceutical manufacturing, cells are having to learn to do without animal components whenever possible. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416879null XML http://www.ptasiapacific.com/ptasiapacific/Formulation/Skin-penetration-of-terpenes/ArticleStandard/Article/detail/417866?ref=25 Terpenes are widely used in topical preparations. This paper focuses on the skin penetration of terpenes depending on their physicochemical properties and influence of the type of dermatological vehicle that was used. The structure of human skin and the skin penetration process is also briefly described. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417866null XML http://www.ptasiapacific.com/ptasiapacific/Drug+Delivery/Skin-penetration-of-terpenes/ArticleStandard/Article/detail/422109?ref=25 This paper focuses on the skin penetration of terpenes depending on their physicochemical properties and influence of the type of dermatological vehicle that was used. 2007-02-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/172007/422109/Cal_flash.jpg XML http://www.ptasiapacific.com/ptasiapacific/Drug+Delivery/Developing-nanoparticle-drug-carriers/ArticleStandard/Article/detail/417838?ref=25 Nanoparticulate drug carriers include a class of particles made of polymers or lipids that — because of their size and chemical composition —permit systemic and local treatment. 2007-01-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417838/main_main.jpg http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417838null XML http://www.ptasiapacific.com/ptasiapacific/Biopharmaceuticals/A-New-Year-for-biotech/ArticleStandard/Article/detail/416866?ref=25 There are currently several hundred biotech-based drugs in clinical trials, representing around a quarter of all drugs in development — a proportion that looks set to increase. 2007-01-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416866null XML http://www.ptasiapacific.com/ptasiapacific/Ingredients/The-effect-of-storage-conditions-on-the-physical-s/ArticleStandard/Article/detail/417895?ref=25 Water interacts with pharmaceutical solids at virtually all stages of manufacture, from synthesis of raw materials to the storage of the final dosage form. The interactions of water with powders is, therefore, a major factor in the formulation, processing and product performance of solid pharmaceutical dosage forms. 2007-01-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417895/main_main.jpg http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417895null XML http://www.ptasiapacific.com/ptasiapacific/Formulation/The-effect-of-storage-conditions-on-the-physical-s/ArticleStandard/Article/detail/417868?ref=25 Water interacts with pharmaceutical solids at virtually all stages of manufacture, from synthesis of raw materials to the storage of the final dosage form. The interactions of water with powders is, therefore, a major factor in the formulation, processing and product performance of solid pharmaceutical dosage forms. 2007-01-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417868/main_main.jpg http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417868null XML http://www.ptasiapacific.com/ptasiapacific/Analytical/The-effect-of-storage-conditions-on-the-physical-s/ArticleStandard/Article/detail/416621?ref=25 Water interacts with pharmaceutical solids at virtually all stages of manufacture, from synthesis of raw materials to the storage of the final dosage form. The interactions of water with powders is, therefore, a major factor in the formulation, processing and product performance of solid pharmaceutical dosage forms. 2007-01-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416621/main_main.jpg http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416621null XML http://www.ptasiapacific.com/ptasiapacific/Formulation/Developing-nanoparticle-drug-carriers/ArticleStandard/Article/detail/417869?ref=25 Nanoparticulate drug carriers include a class of particles made of polymers or lipids that — because of their size and chemical composition —permit systemic and local treatment. 2007-01-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417869/main_main.jpg http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417869null XML http://www.ptasiapacific.com/ptasiapacific/Dosage+Forms/A-New-Year-for-biotech/ArticleStandard/Article/detail/416873?ref=25 There are currently several hundred biotech-based drugs in clinical trials, representing around a quarter of all drugs in development — a proportion that looks set to increase. 2007-01-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416873null XML http://www.ptasiapacific.com/ptasiapacific/Biopharmaceuticals/Ensuring-a-culture-of-quality/ArticleStandard/Article/detail/416865?ref=25 The concept of quality should not only apply to the manufacture of the media — it should also continue throughout the product's lifetime of usage. 2007-01-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416865null XML http://www.ptasiapacific.com/ptasiapacific/Dosage+Forms/Ensuring-a-culture-of-quality/ArticleStandard/Article/detail/416880?ref=25 The concept of quality should not only apply to the manufacture of the media — it should also continue throughout the product's lifetime of usage. 2007-01-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416880null XML http://www.ptasiapacific.com/ptasiapacific/APIs/The-effect-of-storage-conditions-on-the-physical-s/ArticleStandard/Article/detail/416457?ref=25 Water interacts with pharmaceutical solids at virtually all stages of manufacture, from synthesis of raw materials to the storage of the final dosage form. The interactions of water with powders is, therefore, a major factor in the formulation, processing and product performance of solid pharmaceutical dosage forms. 2007-01-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416457/main_main.jpg http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416457null XML http://www.ptasiapacific.com/ptasiapacific/Manufacturing+and+Processing/Artificial-intelligence-the-key-to-process-underst/ArticleStandard/Article/detail/422110?ref=25 In recent years, AI has become important in a number of fields in helping to make better use of information, increasing efficiency and enhancing productivity. 2007-01-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/172007/422110/main_main.jpg http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/172007/422110/Matas_flash.jpg XML http://www.ptasiapacific.com/ptasiapacific/The-effect-of-storage-conditions-on-the-physical-s/ArticleStandard/Article/detail/417830?ref=25 Water interacts with pharmaceutical solids at virtually all stages of manufacture, from synthesis of raw materials to the storage of the final dosage form. The interactions of water with powders is, therefore, a major factor in the formulation, processing and product performance of solid pharmaceutical dosage forms. 2007-01-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417830/main_main.jpg http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417830null XML http://www.ptasiapacific.com/ptasiapacific/Dosage+Forms/Ensuring-a-culture-of-quality/ArticleStandard/Article/detail/416872?ref=25 The concept of quality should not only apply to the manufacture of the media — it should also continue throughout the product's lifetime of usage. 2007-01-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416872null XML http://www.ptasiapacific.com/ptasiapacific/Manufacturing+and+Processing/Artificial-intelligence-the-key-to-process-underst/ArticleStandard/Article/detail/417904?ref=25 In recent years, AI has become important in a number of fields in helping to make better use of information, increasing efficiency and enhancing productivity. 2007-01-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417904/main_main.jpg http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417904null XML http://www.ptasiapacific.com/ptasiapacific/Dosage+Forms/A-New-Year-for-biotech/ArticleStandard/Article/detail/416881?ref=25 There are currently several hundred biotech-based drugs in clinical trials, representing around a quarter of all drugs in development — a proportion that looks set to increase. 2007-01-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416881null XML http://www.ptasiapacific.com/ptasiapacific/PAT/Artificial-intelligence-the-key-to-process-underst/ArticleStandard/Article/detail/417949?ref=25 In recent years, AI has become important in a number of fields in helping to make better use of information, increasing efficiency and enhancing productivity. 2007-01-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417949/main_main.jpg http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417949null XML http://www.ptasiapacific.com/ptasiapacific/Biopharmaceuticals/New-age-therapies/ArticleStandard/Article/detail/416867?ref=25 Why do the biotech ventures mange to have such promising drug candidates while pharmaceutical R&D is facing a drug deficit? 2006-12-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416867null XML http://www.ptasiapacific.com/ptasiapacific/PAT/A-guide-to-EFPIAs-Mock-P2-document/ArticleStandard/Article/detail/417950?ref=25 EFPIA's 'Mock P.2' document aims to show how the role of 'quality risk management' and process analytical technology as an enabler for quality by design can be presented in a common technical document format. This article summarizes the main features of this document, and explains the key concepts and principles used. 2006-12-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417950null XML http://www.ptasiapacific.com/ptasiapacific/Packaging+and+Labelling/Microstructured-transdermal-systems-for-intraderma/ArticleStandard/Article/detail/417934?ref=25 The needle and syringe have long been the standard delivery technology for vaccines. However, a confluence of market factors is driving new interest in alternative delivery systems that hold the potential to meet one or more of the following goals: improved antigen utilization, higher quality immune response, better stability and improved patient acceptance. Of particular interest are microneedle systems, otherwise referred to as microstuctured transdermal systems (MTS), that provide for targeted delivery of the vaccine formulation directly to antigen-presenting cells within the epidermis. This article provides a brief overview of MTS technology with an emphasis on solid-coated MTS for vaccine delivery. 2006-12-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417934null XML http://www.ptasiapacific.com/ptasiapacific/Dosage+Forms/Virus-removal-by-filtration-points-to-consider/ArticleStandard/Article/detail/416883?ref=25 Virus safety of biotech- and plasma-derived therapeutics is ensured through complementary manufacturing and quality control measures that include the control and monitoring of raw materials, the validation and implementation of effective virus clearance technology and the monitoring of final filled product for the presence of virus. Virus filtration, which is considered a robust and effective virus clearance technology, is a common unit operation in the manufacture of biologicals. In this article, we review the points that must be considered when selecting a virus-retentive filter. The areas covered include regulatory considerations; selecting, optimizing and validating a virus filtration step; and process scale implementation — areas that are critical to users of virus filters. 2006-12-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416883null XML http://www.ptasiapacific.com/ptasiapacific/Drug+Delivery/Microstructured-transdermal-systems-for-intraderma/ArticleStandard/Article/detail/417839?ref=25 The needle and syringe have long been the standard delivery technology for vaccines. However, a confluence of market factors is driving new interest in alternative delivery systems that hold the potential to meet one or more of the following goals: improved antigen utilization, higher quality immune response, better stability and improved patient acceptance. Of particular interest are microneedle systems, otherwise referred to as microstuctured transdermal systems (MTS), that provide for targeted delivery of the vaccine formulation directly to antigen-presenting cells within the epidermis. This article provides a brief overview of MTS technology with an emphasis on solid-coated MTS for vaccine delivery. 2006-12-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417839null XML http://www.ptasiapacific.com/ptasiapacific/Dosage+Forms/New-age-therapies/ArticleStandard/Article/detail/416874?ref=25 Why do the biotech ventures mange to have such promising drug candidates while pharmaceutical R&D is facing a drug deficit? 2006-12-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416874null XML http://www.ptasiapacific.com/ptasiapacific/Manufacturing+and+Processing/A-guide-to-EFPIAs-Mock-P2-document/ArticleStandard/Article/detail/417905?ref=25 EFPIA's 'Mock P.2' document aims to show how the role of 'quality risk management' and process analytical technology as an enabler for quality by design can be presented in a common technical document format. This article summarizes the main features of this document, and explains the key concepts and principles used. 2006-12-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417905null XML http://www.ptasiapacific.com/ptasiapacific/Dosage+Forms/Microstructured-transdermal-systems-for-intraderma/ArticleStandard/Article/detail/416884?ref=25 The needle and syringe have long been the standard delivery technology for vaccines. However, a confluence of market factors is driving new interest in alternative delivery systems that hold the potential to meet one or more of the following goals: improved antigen utilization, higher quality immune response, better stability and improved patient acceptance. Of particular interest are microneedle systems, otherwise referred to as microstuctured transdermal systems (MTS), that provide for targeted delivery of the vaccine formulation directly to antigen-presenting cells within the epidermis. This article provides a brief overview of MTS technology with an emphasis on solid-coated MTS for vaccine delivery. 2006-12-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416884null XML http://www.ptasiapacific.com/ptasiapacific/Dosage+Forms/New-age-therapies/ArticleStandard/Article/detail/416882?ref=25 Why do the biotech ventures mange to have such promising drug candidates while pharmaceutical R&D is facing a drug deficit? 2006-12-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416882null XML http://www.ptasiapacific.com/ptasiapacific/Ingredients/Terahertz-applications-for-the-analysis-of-solid-d/ArticleStandard/Article/detail/417897?ref=25 This article investigates pharmaceutical applications of terahertz technology, specifically using techniques for solid dosage form analysis such as pulsed spectroscopy (to generate physical information and detect API changes) and pulsed imaging (to locate formulation impurities, and regulate tablet coating quality and thickness). 2006-11-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/152007/417897null XML http://www.ptasiapacific.com/ptasiapacific/Dosage+Forms/The-fall-and-rise-of-biopharma/ArticleStandard/Article/detail/416885?ref=25 The ¤9.5 billion therapeutic antibody market comprises over a dozen antibodies that have been generated using recombinant genetic methods developed over the last 20 years. 2006-11-01T05:00:00Z http://www.ptasiapacific.com/ptasiapacific/data/articlestandard/ptasiapacific/142007/416885null XML